Total Internal Reflection Fluorescence
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TIRF Applications include:
- Single molecule detection, including smFRET
- Super resolution microscopies
- Cell membrane studies
- Molecular diagnostics
- Analysis of biomolecular interactions
- Monitoring real-time kinetics of biomolecular interactions
- Real-time TIRF microarrays
- Combined DNA, RNA, protein, and metabolite arrays
- Studies of protein-protein and protein-DNA interactions
- Studies of surface supported membranes
- Dynamics of lipid rafts studies
- Nanoengineering
- Bioassay development, and more ...
TIRF Microscopy Application Notes
Application note brochures and PDF reprints of selected articles published by our customers, who used our pTIRF and lgTIRF systems as accessories for fluorescence microscopes.
TIRF Spectroscopy Application Notes
PDF reprints of selected articles published by our customers, who used our TIRF flow system TA1004 as accessory for fluorometers.
TIRF Spectroscopy Application Note 1
A Label-Free Continuous Total-Internal-Fluorescence-Based Immunosensor
TIRF Spectroscopy Application Note 3
Enzymatic lipid removal from surfaces—lipid desorption by a pH-induced “electrostatic explosion”
TIRF Spectroscopy Application Note 5
Adsorption of Poly(ethylene glycol)-Modified Lysozyme to Silica
